Publications

(67) Ma. Y.; Persi, L.; Yan, S.; Lee, S.-S.; Baumgartner, M.*; Yamakoshi, Y.*: Conditionally Activated ROS Generation by MMP2/9-Specific C₆₀-Based Fluorescence Probes. Small 2025, Just Accepted.

(66) Fracassi, A.; Qiao, H.; Lowell, A.; Cao, J.; Bode, J.; Masai, H.; Yoshizawa-Sugata, N.; Zhou, R.*; Yamakoshi, Y.*: Natural and Synthetic LDL-Based Imaging Probes for the Detection of Atherosclerotic Plaques. ACS Pharmacology & Translational Science 2025, Just Accepted.

(65) Castanyer, C.; Çelik, Ç.; Artigas, A.; Roglans, A.; Quintana, A. P.*; Stasyuk, A. J.*; Yamakoshi, Y.*; Solà, M.*: Enhancement of photoinduced reactive oxygen species generation in open-cage fullerenes. Chem. Sci. 2025, ASAP.

(64) Yamakoshi, Y.: ROS Generation by Fullerenes for Biology and Nanotechnology. J. Synth. Org. Chem. 2024, 82, 1125-1136.
 

(63) Takagi, H.; Çelik, Ç.; Fukuda, R.; Guo, Q.; Higashino, T.; Imahori, H.; Yamakoshi, Y.; Murakami, T.*: Interaction of a pyrene derivative with cationic [60] fullerene in phospholipid membranes and its effects on photodynamic actions. Beilstein J. Org. Chem. 2024, 20, 2732-2738.

(62) Nemeth, T.; Pallier, A.; Çelik, Ç.; Garda, Z,; Yoshizawa-Sugata, N.*; Masai, H.*; Tóth, É.*; Yamakoshi, Y.*: Water-Soluble Mn(III)-Porphyrins with High Relaxivity and Photosensitization. ACS Chem. Biomed. Imaging 2024.

(61) Ma, Y.; Persi, L.; Yamakoshi, Y.*: Synthesis and characterization of water-soluble C₆₀–peptide conjugates. Beilstein J. Org. Chem. 2024, 20, 777-786.

(60) Nemeth, T.; Yoshizawa-Sugata, N.; Pallier, A.; Tajima, Y.; Ma, Y.; Tóth, É.*; Masai, H.*; Yamakoshi, Y.*: Water-Soluble Gd (III)–Porphyrin Complexes Capable of Both Photosensitization and Relaxation Enhancement. ACS Chem. Biomed. Imaging, 2023, 1, 157-167.

(59) Ray, A.; Passiu, C.; Nasuda, M.; Ramakrishna, S. N.; Rossi, A.; Kuzuya, A.; Spencer, N. D.; Yamakoshi, Y.*: Reactive-Oxygen-Species-Mediated Surface Oxidation of Single-Molecule DNA Origami by an Atomic Force Microscope Tip-Mounted C₆₀ Photocatalyst. ACS Nano 2021, 15, 19256-19265.

(58) Liosi, K; Stasyuk, A. J.; Masero, F.; Voityuk, A. A.; Nauser, N.; Mougel, V.*; Sola, M.*; Yamakoshi, Y.*: Unexpected Disparity in Photoinduced Reactions of C₆₀ and C₇₀ in Water with the Generation of O₂•^– or ¹O₂. JACS Au, 2021, 1, 1601-1611 [selected as Paper of Month by Spanish Biophysical Society].

(57) Fracassi, A.;^# Ray, A.;^# Nakatsuka, N.; Passiu, C.; Tanriver, M.; Schauenburg, D.; Scherrer, S.; Ouald Chaib, A.; Mandal, J.; Ramakrishna, S. N.; Bode, J. W.; Spencer, N. D.; Rossi, A.; and Yamakoshi, Y.*: KAT ligation for rapid and facile covalent attachment of biomolecules to surfaces. ACS Appl. Mater. Interfaces 2021, 13, 29113–29121 (^#equal contribution).

(Preprint 2) Fracassi, A., Ray, A., Nakatsuka, N., Passiu, C., Tanriver, M., Schauenburg, D., Scherrer, S., Ramakrishna, S.N, Bode, J., Spencer, N. D., Rossi, A., Yamakoshi, Y.: KAT Ligation for Rapid and Facile Covalent Attachment of Biomolecules to Surfaces. 2021 external page link 

(Preprint 1) Ray, A., Passiu, C., Ramakrishna S. N., Rossi, A., Kuzuya, A., Spencer, N. D., Yamakoshi Y.: Local, Single-Molecule Oxidative Cleaving of DNA Origami by C₆₀ on an AFM Tip. 2021 external page link

(56) Fracassi, A.; Cao, J.; Yoshizawa-Sugata, N.; Tóth, É. Archer, C.; Gröninger, O.; Ricciotti, E.; Tang, S. Y.; Handschin, S.; Bourgeois, J.-P., Ray, A.; Liosi, K.; Oriana,S.; Stark, W.; Masai, H.; Zhou, R.*; Yamakoshi, Y.*: LDL-mimetic lipid nanoparticles prepared by surface KAT ligation for in vivo MRI of atherosclerosis. Chem. Sci. 2020, 11, 11998-12008 [selected as inside cover].  external page link

(55) Ray, A.; Liosi, K.; Ramakrishna, S. N.; Spencer, N. D.; Kuzuya, A.*; Yamakoshi, Y.*: Single-Molecule AFM Study of DNA Damage by ¹O₂ Generated from Photoexcited C₆₀. J. Phys. Chem. Lett. 2020, 11, 7819–7826. external page link

(54) Semivrazhskaya, O.; Aroua, S.; Yulikov M.; Romero-Rivera, A.; Stevenson S.; Garcia-Borràs, M.; Osuna, S.*; Yamakoshi, Y.*: Regioselective Synthesis and Characterization of Tris- and Tetra-Prato Adducts of M₃N@C₈₀ (M = Y, Gd). J. Am. Chem. Soc. 2020, 142, 12954-​12965. external page link

(53) Semivrazhskaya, O.; Romero-Rivera, A.; Aroua, S.; Troyanov, S. I.; Garcia-Borràs, M.; Stevenson, S.; Osuna, S.*; Yamakoshi, Y.*: Structures of Gd₃N@C₈₀ Prato Bis-Adducts: Crystal Structure, Thermal Isomerization, and Computational Study. J. Am. Chem. Soc. 2019, 141, 10988-10993. external page link

(52) Liosi, K.; Romero-Rivera, A.; Semivrazhskaya, O.; Caniglia, C. D.; Garcia-Borràs, M.; Trapp, N.; Osuna, S.*; Yamakoshi, Y.*: Site-Selectivity of Prato Additions to C₇₀: Experimental and Theoretical Studies of a New Thermodynamic Product at the dd-[5,6]-Junction. Org. Lett. 2019, 21, 5162-5166. external page link

(51) Aroua, S.; Ray, A.; Ebert, M.-O.; Yamakoshi, Y.*: Effect of Temperature and Solvent on the Structure of Amide Cavitands. Helv. Chim. Acta 2019, 102, e1900043. external page link

(50) Aroua, S.; Lowell, A. N.; Ray, A.; Trapp, N.; Schweizer, W. B.; Ebert, M.-O.; Yamakoshi, Y.*: Larger Substitution on Amide Cavitands Induce Bigger Cavities. Org. Lett. 2019, 21, 201-205. external page link

(49) Oriana, S.;^# Fracassi, A.;^# Archer, C.; Yamakoshi, Y.*: Covalent Surface Modification of Lipid Nanoparticles by Rapid Potassium Acyltrifluoroborate Amide Ligation, Langmuir 2018, 34, 13244-13251 (^#equal contribution). external page link

(48) Tiu, E. G. V.; Liosi, K.; Aroua, S.; Yamakoshi, Y.*: Micelle vs Vesicle Formation Controlled by Distal Functionalization of C₆₀-PEG Conjugates, J. Mater. Chem. B 2017, 5, 6676-6680.

(47) Royappa, A. R.; Ayer, M.; Fracassi, A.; Ebert, M. O. Aroua, S.; Yamakoshi, Y.*: Conformationally Selective Synthesis of Mononitrocalix[4]arene in Cone or Partial Cone, Helv. Chim. Acta 2017, 100, 5.

(46) Oriana, S.; Cai, Y.; Bode, J. W.; Yamakoshi, Y.*: Synthesis of Tri-functionalized MMP2 FRET Probes Using a Chemo-selective and Late-stage Modification of Unprotected Peptides, Org. Biomol. Chem. 2017, 15, 1792-1800.external page link

(45) Aroua, S.; Tiu, E. G. V.; Ishikawa, T.; Yamakoshi, Y.*: Well-Defined Amphiphilic C₆₀-PEG Conjugates: Water Soluble and Thermoresponsive Materials, Helv. Chim. Acta, 2016, 99, 10, 805-813.

(44) Kumar, R.; Gleißner, E.; Tiu, E. G. V.; and Yamakoshi, Y.*: C₇₀ as a Photocatalyst for Oxidation of Secondary Benzylamines to Imines, Org. Lett. 2016, 18, 184-187.

(43) Kumar, R.; Ramakrishna, S. N.; Naik, V. V.; Chu, Z.; Drew, M. E.; Spencer, N. D.; Yamakoshi, Y.*: Versatile Method for AFM-tip Functionalization with Biomolecules: Fishing a Ligand by Means of an in situ Click Reaction, Nanoscale, 2015, 7, 6599-6606.

(42) Aroua, S.; Tiu, E. G. V.; Ayer, M.; Ishikawa, T.; Yamakoshi, Y.*: RAFT Synthesis of Poly(vinylpyrrolidone) Amine and Preparation of a Water-soluble C₆₀-PVP Conjugate, Polymer Chem. 2015, 6, 2616–2619.

(41) Aroua, S.; Garcia-Borràs, M.; Bölter M. F.;, Osuna, S.*; Yamakoshi, Y.*: Endohedral Metal-Induced Regioselective Formation of Bis-Prato Adduct of Y₃N@I_h-C₈₀ and Gd₃N@I_h-C₈₀, J. Am. Chem. Soc. 2015, 137, 58-61.

(40) Aroua, S.; Garcia-Borras, M.; Osuna, S.*; Yamakoshi, Y.*: Essential Factors for Controlling the Equilibrium in Reversible Rearrangement of M₃N@I_h-C₈₀ Fulleropyrrolidines: Exohedral Functional Groups versus Endohedral Metal Clusters, Chem. Eur. J. 2014, 20, 14032-14039.

(39) Yamakoshi, Y.*; Aroua, S.; Nguyen, T.-M.; Iwamoto, Y.; Ohnishi, T.: Water-soluble Fullerene Materials for Bioapplication, Faraday Discuss. 2014, 173, 287-296.

(38) Aroua, S.; Schweizer, W. B.; Yamakoshi, Y.*: C₆₀ Pyrrolidine Bis-carboxylic Acid Derivative as a Versatile Precursor for Biocompatible Fullerenes, Org. Lett. 2014, 16, 1688-1691.

(37) Oriana, S.; Aroua, S.; Söllner, J. O. B.; Ma, X.; Iwamoto, Y.; Yamakoshi, Y.*: Water-soluble C₆₀– and C₇₀–PVP Polymers for Biomaterials with Efficient ¹O₂ Generation, Chem. Comm. 2013, 49, 9302–9304.external page link

(36) Aroua, S.; Yamakoshi, Y.*: Prato Reaction of M₃N@I_h-C₈₀ (M = Sc, Lu, Y, Gd) with Reversible Isomerization, J. Am. Chem. Soc. 2012, 134, 20242–20245.

(35) Lowell, A. N.; Qiao, H.; Liu, T.; Ishikawa, T.; Zhang, H.; Oriana, S.; Wang, M.; Ricciotti, E.; Fitzgerald, G. A.; Zhou, R.*; Yamakoshi, Y.*: Functionalized Low-density Lipoprotein Nanoparticles for in vivo Enhancement of Atherosclerosis on Magnetic Resonance Images. Bioconjugate Chem. 2012, 23, 2313–2319.

(34) Drew, M. E.; Konicek, A. R.; Jaroenapibal, P.; Carpick, R. W.*; Yamakoshi, Y.*: Nanocrystalline Diamond AFM Tips for Chemical Force Spectroscopy: Fabrication and Photochemical Functionalization. J. Mater. Chem. 2012, 22, 12682–12688.external page link

(33) Yamakoshi, Y.*; Qiao, H.; Lowell, A. N.; Woods, M.; Paulose, B.; Nakao, Y.; Zhang, H.; Liu, T.; Lund-Katz, S.; Zhou, R.*:LDL-based Nanoparticles for Contrast Enhanced MRI of Atheroplaques in Mouse Models.Chem. Comm. 2011, 47, 8835–8837.external page link

(32) Takamatsu, D.; Fukui, K.*; Aroua, S.; Yamakoshi, Y.*: Photoswitching Tripodal Single Molecular Tip for Noncontact AFM Measurements: Synthesis, Immobilization, and Reversible Configurational Change on Gold Surface. Org. Biomol. Chem. 2010, 8, 3581–3808. [inside front cover] external page link

(31) Drew, M. E.; Chworos, A.; Oroudjev, E.; Hansma, H.; Yamakoshi, Y.*: A Tripod Molecular Tip for Single Molecule Ligand－Receptor Force Spectroscopy by AFM. Langmuir 2010, 26, 7117–7125.external page link

(30) Nakaoka, R.*; Yamakoshi, Y.; Isama, K.; Tsuchiya, T.: Study for Enhancing Differentiation Level of Osteoblasts by Surface Chemistry Prepared by Self-Assembled Monolayers. J. Biomed. Mat. Res.: Part A 2010, 94A, 524–532.

(26) Takamatsu, D.; Yamakoshi, Y.*; Fukui, K.*: Photoswitching Behavior of Nobel Single Molecular Tip of Noncontact Atomic Force Microscopy Designed for Chemical Identification. J. Phys. Chem. B 2006, 110, 1968－1970. (highlighted in Photonics Spectra Magazine)

(24) Azov, V. A.; Beeby, A; Cacciarini,M.; Cheetham,A. G.; Diederich, F.*; Frei, M.; Gimzewski, J. K.; Gramlich, V.; Hecht, B.; Jaun, B.; Latychevskaia, T.; Lieb, A.; Lill, Y.; Marotti, F.; Schlegel, A.; Schlittler, R. R.; Skinner, P. J.; Seiler, P.; Yamakoshi, Y.: Resorcin[4]arene Cavitand-Based Molecular Switches. Adv. Function. Mater. 2006, 16, 147–156. (inside front cover)

(23) Nakazawa, K.*; Yamakoshi, Y.; Tsuchiya, T.; Ohno, Y.: Purification and aqueous phase atomic force microscopic observation of recombinant P2X2 receptor. Eur. J. Pharmacol. 2005, 518, 107－110.

(20) Azov, V. A.; Skinner, P. J.; Yamakoshi, Y.; Seiler, P.; Gramlich, V.; Diederich, F.*: Functionalized and Partially or Differentially Bridged Resorcin[4]arene Cavitands: Synthesis and Solid-state Structures.Helv. Chim. Acta 2003, 86, 3648－3670.

(15) Yamakoshi, Y.; Schlittler, R. R.; Gimzewski, J. K.*; Diederich, F.*: Synthesis of Molecular-Gripper-Type Dynamic Receptors and STM Imaging of Self-Assembled Monolayer on Gold. J. Mat. Chem. 2001, 11, 2895－2897.

(28) Lee, J.; Yamakoshi Y.; Hughes, J. B.; Kim, J. H.*: Mechanism of C₆₀ Photochemistry in the Aqueous Phase: Fate of Triplet State and Radical Anion and Production of Reactive Oxygen Species. Environ. Sci. Technol. 2008, 42, 3459－3464.

(27) Iwamoto, Y.; Yamakoshi, Y.*: Highly Water-soluble C₆₀-NVP Copolymer: A Potential Material for Photodynamic Therapy. Chem. Commun. 2006, 4805–4807. (selected as a hot article) external page link

(21) Okada, E.; Komazawa, Y.; Kurihara, M.; Inoue, H.; Miyata, N.; Okuda, H.; Tsuchiya T.; Yamakoshi, Y.*: Synthesis of C₆₀ Derivatives for Photoaffinity Labeling. Tetrahedraon Lett. 2004, 45, 527–529.

(19) Yamakoshi, Y.*; Umezawa, N.; Ryu, A.; Arakane, K.; Miyata, N.; Goda, Y.; Masumizu, T.; Nagano, T.: Active Oxygen Species Generate from Photoexcited Fullerene (C₆₀) as Potential Medicines: O₂^－● versus¹O₂. J. Am. Chem. Soc. 2003, 125, 12803－12809.

(17) Kai, Y.; Komazawa, Y.; Miyajima, A.; Miyata, N.; Yamakoshi, Y.*: [60]Fullerene as a novel photoinduced antibiotic. Fullerene Nanotubes and Carbon Nanostructures 2003, 11, 79－87.

(14) Yamakoshi, Y.*; Sueyoshi, S.; Miyata, N.: Biological Activity of Photoexcited Fullerene. Bull. Natl. Health Sci. 1999, 117, 50－62.

(13) Sakai, A.*; Yamakoshi, Y.; Miyata, N.: Visible Light Irradiation of [60]Fullerene Causes Killing and Initiation of Transformation in BALB/3T3 Cells. Fullerene Sci. Technol. 1999, 7, 743－746.

(12) Iwata, N.*; Mukai, T.; Yamakoshi, Y.; Hara, S.; Yanase, T.; Shoji, M.; Endo, T.; Miyata, N.: Effect of C₆₀, a Fullerene, on the Activities of Glutathione S-Transferase and Glutathion-related Enzymes.Fullerene Sci. Technol. 1998, 6, 213－226.

(11) Yamakoshi, Y.; Sueyoshi, S.; Fukuhara, K.; Miyata, N.*; Masumizu, T.; Kohno, M.: OH^-● and O₂^-● Generation in Aqueous C₆₀ and C₇₀ Solution by Photoirradiation. An EPR Study. J. Am. Chem. Soc. 1998,120, 12363–12367.

(10) Yamakoshi, Y.; Yagami, T.; Sueyoshi, S.; Miyata, N.: Acridine Adduct of [60]Fullerene with Enhanced DNA-Cleaving Activity. J. Org. Chem. 1996, 61, 7236–7237.

(8) Tsuchiya, T.*; Oguri, I.; Yamakoshi, Y.; Miyata, N.: Novel Harmful Effects of [60]Fullerene on Mouse Embryos in vitro and in vivo. FEBS Lett. 1996, 393, 139－145.

(7) Tsuchiya, T.*; Oguri, I.; Yamakoshi, Y.; Miyata, N.: Effect of [60]Fullerene on the Chondrogenesis in Mouse Embryonic Limb Bud Cell Culture System. Fullerene Sci. Technol. 1996, 4, 989－999.

(6) Tsuchiya, T.*; Yamakoshi, Y.; Miyata, N.: A Novel Promoting Action of Fullerene C₆₀ on the Chondrogenesis in Rat Embryonic Limb Bud Cell-culture System. Biochem. Biophys. Res. Commun. 1995, 206, 885－894.

(5) Sakai, A.*; Yamakoshi, Y.; Miyata, N.: The Effect of Fullerenes on the Initiation and Promotion Stages of BALB/3T3 Cell Transformation. Fullerene Sci. Technol. 1995, 3, 377－388.

(4) Yamakoshi, Y.; Yagami, T.; Fukuhara, K.; Sueyoshi, S.; Miyata, N.*: Solubilization of Fullerenes into Water with Polyvinylpyrrolidone Applicable to Biological Tests. J. Chem. Soc., Chem. Commun. 1994, 517－518.

(29) Miyajima, A.*; Sunouchi M.; Mitshinaga, K.; Yamakoshi, Y.; Usami, M.:Sexing of Postimplantation Rat Embryos in Stored Two-Dimensional Electrophoresis Samples by Polymerase Chain Reaction of an Sry Sequence. J. Toxicol. Sci. 2009, 34, 681－685.

(22) Nagira, T.; Matthew, S. B.; Yamakoshi, Y.; Tsuchiya, T.*: Enhancement of Gap Junctional Intercellular Communication of Normal Human Dermal Fibroblasts Cultured on Polystyrene Dishes Grafted with Poly-N-isopropylacrylamide. Tissue Engineering 2005, 11, 1392－1397.

(25) Nishikawa, K.*; Machida, H.; Yamakoshi, Y.; Ohtomo, R.; Saito, K.; Saito, M.; Tominaga, N.: Polyphosphate Metabolism in an Acidophilic Alga Chlamydomonas acidophila KT-1 (Chlorophyta) under Phosphate Stress. Plant Sci. 2006, 170, 307－313.

(18) Nishikawa, K.*; Yamakoshi, Y.; Uemura, I.; Tominaga, N.: Ultrastructural Changes in Chlamydomonas acidophila (Chlorophyta) Induced by Heavy Metals and Polyposphate Metabolism. FEMS Microbiol. Ecology 2003, 44, 253－259.

(16) Takahashi, T.*; Yamakoshi, Y.; Ge, W.-Y.; Sugita, J.; Okayama, K.; Koizumi, T.: High-Pressure Mediated Asymmetric Diels-Alder Reaction of Chiral Sulfinyl Acrylate Derivatives and Its Application to Chiral Synthesis of (－)-COTC and (－)-Gabosine C. Heterocycles 2002, 56, 209－220.

(9) Yamakoshi, Y.; Ge, W.-Y.; Sugita, J.; Okayama, K.; Takahashi, T.; Koizumi, T.*: High Pressure Mediated Asymmetric Diels-Alder Reaction of Chiral Sulinylacrylate Derivatives with Furan and 2-Methoxyfuran.Heterocycles 1996, 42, 129－133.